All the restaurants, hotels, bars and most of the beaches and tourist attractions are within walking distance. In Puerto Ayora (Santa Cruz), Puerto Baquerizo Moreno (San Cristobal) and Puerto Villamil (Isabela) several businesses offer bicycles for rent if you wish to get one. There are also taxis to take you to the more distant places. Rates are reasonable.
Tour operators usually include transportation in their packages to non-inhabited islands in the Galapagos National Park Preserve. Check the tourism section for more information on the tour modalities in the Galapagos Islands.